Dark spots, or specific, localized areas of hyperpigmentation, are caused by the overproduction of melanin in the skin following everyday triggers like excessive exposure to the sun, acne, hormones, aging, and skin irritation
2-MNG conjugates with some melanin precursors, preventing their integration into melanin polymers, leading to an inhibition of both eumelanin and pheomelanin production, while preserving their ratio and melanocyte integrity [120]
*Correspondence: Xuemei Tong [email protected] This article was submitted to Cellular Endocrinology, a section of the journal Frontiers in Endocrinology These authors have contributed equally to this work Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers
doi: 10.1016/B978-0-12-407865-9.00007-8 128 JiangLZhangHWangCMingFShiXYangM
Therapeutic targeting of PP2A