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Higher doses dont necessarily improve results and may increase the risk of side effects

It's also important to remember that if you have Leber's disease, a specific type of B12 called cyanocobalamin could be harmful to your optic nerve

Statistical analyses were performed using GraphPad Prism 9.1.0 (GraphPad Software, USA) via two-way ANOVA with Tukey's multiple comparison or Dunnet's multiple comparison

It boosts the fibroblast to increase collagen, elastin and hyaluronic acid production, improving texture, elasticity and hydration

When restarting, patients return directly to the maintenance dose of 20 units (1.0 mg) daily