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GHRH-analog and secretagogue schedules commonly run 812 weeks on, followed by 4 weeks off , allowing receptor sensitivity and the IGF-1 axis to reset before another cycle

The process begins within minutes of administration

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Pre-clinical work across skin, lung, liver, and bone models has reported tissue-repair activity, attributed to fibroblast restoration, antioxidant signaling, anti-inflammatory effects, and matrix-protein synthesis

doi:10.1002/1099-0690(200301)2003:1 3.0.CO;2-I