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Doig, 2018), but offers little on the actual origin of LOAD or the driver of abnormal A production and is thus incomplete

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NAC (N-acetylcysteine) is a glutathione precursor with ~30% bioavailability and is well-studied in thyroid disease

Primary antibodies were anti-GFP (Aves labs GFP-1020, 1:1000), anti-Syt1 (Synaptic Systems 105-011

Results Selection of residues and generation of Grx mutants As reviewed recently 3 , structural studies on glutaredoxins revealed several residues that are involved in glutathione interactions (Fig