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These statements have not been evaluated by the FDA and are not intended to diagnose, treat, cure, or prevent any disease

The factors that lead to depletion of glutathione includes natural ageing process, or the external stressors that include chronic exposure to chemical toxins, cadmium exposure, alcohol use, smoking, pollution, strenuous aerobic activities, dietary factors, ultraviolet (UV) radiation exposure, tissue injury as from burns, ischemia, septic shock, surgery, drugs (such as acetaminophen and adriamycin)

Selenium in the prevention of atherosclerosis and its underlying mechanisms

The half-life is 10 minutes

5, 10.1038/srep09018 (2015)