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Thymosin beta-4 represents the endogenous parent peptide from which TB-500 derived fragments originate and is widely studied for its actin-binding behavior and role in cellular migration signaling

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After the Tween 80/Span 20 ratio was optimized, the molar ratio of IPM to the Tween 80/Span 20 mixture was varied as 1:9, 2:8, 3:7, 4:6, 5:5, 6:4, 7:3, 8:2, and 9:1 to select the optimal ratio of IPM to the surfactant mixture

US 8598118, Harding JW, Wright JW, Benoist CC, Kawas LH, Wayman GA, "Hepatocyte growth factor mimics as therapeutic agents", issued 3 December 2013 "Facilitation of hippocampal synaptogenesis and spatial memory by C-terminal truncated Nle1-angiotensin IV analogs"