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Interestingly, the incubation with the antioxidant N-acetylcysteine (NAC) upon treatment with NP4 resulted in reduced levels of apoptosis, suggestive that the cytotoxicity of NP4 is related to intracellular redox homeostasis (Supplementary Fig
Sterile, multi-dose Pfizer vial with 0.9% benzyl alcohol
Key Specs Research context: NNMT interaction, enzyme and pathway assays Common model types: biochemical assays, cell-based pathway studies References: PubChem and PubMed [1,2] Referenced Citations PubChem, 5-Amino-1-methylquinolinium: PubMed, NNMT and metabolic regulation (review and mechanistic context): NNMT Interaction Studies 5-AMINO-1MQ is primarily examined for its inhibitory interaction with NNMT, an enzyme involved in nicotinamide methylation and NAD-related metabolism [1,2]
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