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His research has been primarily focused on the sirtuins, protein-modifying enzymes that respond to changing NAD+ levels and to caloric restriction (CR) with associated interests in chromatin, energy metabolism, mitochondria, learning and memory, neurodegeneration, and cancer

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The body uses vitamin B12 to maintain healthy nerve cells, produce RNA, DNA and red blood cells as well as help iron to function properly

For example, syntaxin binding protein 1 (STXBP1, commonly named Munc18-1) is overexpressed in pheochromocytoma (Houy et al., 2022), whereas expression level of the GTPases Rab3a-c or Rab27a-b and granuphilin (sytl4) is modified in pheochromocytoma, medullary thyroid carcinoma and in somatotroph or corticotroph pituitary tumor (Table 1), (Zhan et al., 2018