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GH/IGF-1, and particularly IGF-1, play various roles in neurons such as neuroprotection, mitochondrial protection, antioxidant defence, and reduction in CNS inflammation (431)
This work underscores the potential of host-directed therapeutics, in conjunction with antibiotics, to improve treatment outcomes
These observations collectively suggest that the underlying pathophysiology of depression needs to be further investigated
Potential Research Applications: pH regulation and buffer system studies Topical antimicrobial and cytotoxicity research Reagent dilution and formulation preparation Laboratory protocol requiring acidic conditions For laboratory use only