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If true, such a scenario would pose a formidable challenge to the research community, because distinguishing a physiological form of an otherwise normal endogenous brain protein from a pathologically misfolded/aggregated conformer is not trivial

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The firing properties of the different classes of cerebellar neurons have been extricated by in vitro and in vivo recordings [4,5,6]

doi:10.1515/CCLM.2007.362

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