Neurodegenerative diseases, including Alzheimers and Parkinsons, are also heavily influenced by oxidative stress, which accelerates the formation of harmful protein aggregates and neuroinflammation ( CHAC1 is a key regulator of cellular stress responses, particularly oxidative stress, apoptosis, and ferroptosis, and it plays a central role in the pathogenesis of a wide range of non-malignant diseases
10.14336/AD.2019.0508 Aging Dis
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Notably, several agents have received regulatory approval in the US, China, and the EU, while others are advancing through Phase II and III trials
This balanced approach can harness the benefits while minimizing uncertainties