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Recent studies on nutrition confirm that children and adolescents prefer products that are sweeter and have more intense flavour than those preferred by adults.127 ,128 In fact, flavour is a major factor in promoting products for the youth market.129 Children prefer higher intensities of sweet taste than adults do and there is evidence that sweet taste preferences are innate in humans.130 ,131 The blinding effects of sugar may be due not only to its impact on the pH of tobacco but also to its analgesic and opiate-like properties.132 The brain circuitry activated from tasting sweet substances overlaps with the circuitry mediating the addictive nature of drugs, such as opiates.132 ,133 Thus, children's liking of the sweetness intensity is positively associated with pain tolerance.134 Our findings confirm that mint-flavoured and wintergreen-flavoured products may be especially effective in making tobacco more palatable to novices, possibly contributing to the initiation and maintenance of ST use.135 We found that mint flavouring plays a particularly important role in initiation of smokeless use and subsequent dependence