Experimental and Clinical Cancer Research CR 36 (1), 47
Kidney-Type glutaminase inhibitor Hexylselen selectively kills Cancer cells via a Three-Pronged mechanism
Abstract:Chronic hyperglycemia in diabetics causes microvascular damage through four mechanisms of biochemical changes, including activated protein kinase C (PKC) pathway, activated hexosamine pathway, increased polyol pathway, and increased advanced glycation end-products (AGEs), all of which will increase Reactive Oxygen Species (ROS) levels
Results There were no differences in oxidative stress biomarkers between treatment groups at baseline
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