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Addressing Common Absorption Barriers Things like stomach problems, some meds, and getting older can make it hard to absorb vitamin B12

Still, most people move through a fairly predictable set of stages, and knowing them helps you set realistic expectations

[95] Intramuscular or intravenous injection [edit] Injection of hydroxycobalamin is often used if digestive absorption is impaired, [2] but this course of action may not be necessary with high-dose oral supplements (such as 0.51.0 mg or more), [97] [98] because with large quantities of the vitamin taken orally, even the 1% to 5% of free crystalline B 12 that is absorbed along the entire intestine by passive diffusion may be sufficient to provide a necessary amount

Avoid repeated freeze-thaw cycles as this can degrade the peptide

Sublingual tablets come in 500 or 1000 mcg dosages