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10.1016/S0972-6292(16)30753-7 117

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Stern JH, Smith GI, Chen S, Unger RH, Klein S, Scherer PE

Example A great example of tolerance is in the story of Brett Favre, a Hall of Fame quarterback who played for the Green Bay Packers 1991-2010

With regard to ALD, although alcohol-induced hepatotoxicity and oxidative stress are the key components contributing to its pathogenesis, recent studies have clearly shown that the immune response might also substantially contribute to the development of ALD, including its inflammatory component, alcoholic steatohepatitis (ASH) (Fig