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The pathogenesis of SCARs involves T cell receptors recognizing drug antigens presented by human leukocyte antigens, triggering the activation of distinct T cell subsets

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In these cases, Dr Brumby-Rendell will need to make a larger incision to prevent the recurrence of the condition and promote proper healing

These findings address the limitations of clinical trials, provide a basis for safety monitoring of the combined use of ipilimumab and nivolumab, and offer valuable evidence for further research and clinical application of this drug combination