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In general, it is assumed that the two main limiting factors are the levels of cysteine and of the enzyme gamma-glutamyl-cysteine synthetase (also known as glutamate-cysteine ligase)

Fecal microbiota transplantation is also being explored in ME/CFS research due to indications that the microbiome may significantly impact the disease, particularly its neurological symptoms [160, 161]

doi: 10.1016/S2213-8587(15)00284-3 14 DevriesM

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