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And it's hard to get animals to self-administer nicotine the way they will with cocaine. More significantly, there is increasing evidence that nicotinic receptor function may play a significant role and nicotine may be a therapeutic target in neurodegenerative disorders such as Alzheimers and dementia, as well as schizophrenia, Parkinson's disease, anxiety disorders, and attention deficit-hyperactivity disorder (ADHD)
Body mass index, waist circumference, diabetes, and risk of liver cancer for U.S
A dose-response relationship also exists: smoking one pack per day increases risk several times, while two packs or more multiplies the risk exponentially
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