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It typically presents as macrocytic megaloblastic anemia and neurological impairments, including sensory and motor disfunctions, predominantly in the lower extremities, ataxia, and in more advanced stages cognitive decline progressing to dementia, as well as psychiatric disturbances (Green et al., 2017)
Pellissier et al
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Mast Cell Activation Syndrome (MCAS): KPV's ability to reduce cytokine secretion from mast cells has led to interest in its use for MCAS, where dysregulated mast cell degranulation produces systemic inflammatory symptoms
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