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The treatment, in this case, usually follows by means of having daily injections for a week or so, then injections every few days for a month, after which maintenance doses are usually given every one to two months for life
Evaluation: Body fat (DXA scanning) Lean mass Insulin sensitivity Energy expenditure What they found: The combination showed an additive effect on fat reduction vs monotherapy AOD-9604 partially protected lean mass during GLP-1-induced weight reduction Increased energy expenditure in combination (~3 % vs GLP-1 alone) No new safety signals Why it matters: It validates the concept of combination , the idea that AOD-9604 may not work on its own, but can add value in combination with incretin agonists
Methionine It is an essential amino acid which means it cannot be synthesized in our body so we must get it from other sources
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