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Sheibani V, Rajizadeh MA, Bejeshk MA, Haghparast E, Nozari M, Esmaeili-Mahani S, et al

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Unlike NSAIDs that mask symptoms by blocking prostaglandin synthesis, peptides modulate inflammation at the transcriptional level and enhance healing cascades

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In vitro studies on human mononuclear cells also showed that alogliptin (0.5, 1 and 5 nM) treatment for 24 h exhibited a decrease in TLR-4 mediated increase in IL-1 and IL-6 [55]