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Wilson KM, Klein JD, Blumkin AK, Gottlieb M, Winickoff JP

"Tobacco (Nicotiana tabacum L.) A model system for tissue culture interventions and genetic engineering" (PDF)

Protecting public health: More than just regulation Regulation alone is not enough

Also, in the second half of the 18th century, snuff became popular, imported from Spain, France and Germany

Their cargo included tobacco that they wholesaled to local and regional tobacconists, including Lancaster snuff maker Christopher Demuth (1738-1818) who, between 1803 and 1813, purchased an average of seventeen thousand pounds of tobacco annually from the firm