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HU2021/Z/AAM0521-01) and the National Institute of Health Guide for the Care and Use of Laboratory Animals, 8th Edition (NIH publication no.85 23, revised 1985)

PWL080, meilunbio, China)

inclusion formation, subcellular localization, and insolubility (Cohen et al., 2017) and WT forms of TDP-43 and SOD1 can be induced to misfold and aggregate in neuronal cells (Iguchi et al., 2012