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The life cycle of skin melanocytes consists of several steps, including lineage specification from embryonic neural crest cells (melanoblasts), migration and proliferation of melanoblasts, differentiation of melanoblasts into melanocytes with dendritic morphology 23

Smoking also increases risk by reducing blood flow to spinal structures and impairing tissue repair

Jurusan Farmasi Fakultas Ilmu Kesehatan Universitas Jenderal Soedirman