Because hyperthyroidism is characterized by hypermetabolism, polyphagia, weight loss, PD, and PU are prominent features of the disease.22, 23 Hyperactivity, tachycardia, pupillary dilation, and behavioral changes are also characteristic of the disease and are associated with activation of the sympathetic nervous system
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The number of W-boxes and their distribution patterns highly varied between GST promoters (Figure 3)
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Therefore, the clearance of senescent cells through apoptosis is one of the proposed mechanisms to reduce the burden imposed by the presence of senescent cells and in consequence, prevent age-related diseases and ultimately revert aging 3
