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At the same time, TB-500 activates actin polymerization, a cytoskeletal protein, allowing fibroblasts and endothelial cells to migrate extremely rapidly through these newly formed pathways directly to the site of injury

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Due to the distinct position of the conjugated N-terminal lipid between Cagri-CTR and Cagri-AMY 1 R, we also determined a structure of CTR-Gs in complex with an analogue of Cagri that lacked the lipid modification (CagriBB) to interrogate the contribution of the acylation to the conformation of Cagri-CTR complex

Consider reducing dose to see if effects diminish

This is crucial for ensuring that muscle and cardiac tissue heal with flexibility rather than stiff, non-functional scar tissue