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Regarding weight management , NHS guidance is unequivocal: B12 supplementation is not recommended as a weight loss intervention

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This essential amino acid plays a vital role in breaking down fats in the liver and helps lower cholesterol levels

Safety and Research Limitations Importantly, No adequate clinical evidence defines safe human exposure, maximum tolerated dose, reproductive toxicity, carcinogenicity, genotoxicity, cardiovascular risk, liver safety, kidney safety, endocrine effects, or drug interactions