This potentially mimics a more natural pulsatile GH release pattern
Although the number of published studies is still limited, the integration of patient derived primary cells and organoids into OoC systems is emerging as a powerful approach to advance personalized therapy design and mechanistic disease investigation (145)
Numerous researches conducted over the past few years have shown that curcumin inhibits cell growth, metastasis, and proliferation while causing cell death in a variety of malignancies
the use of pro-GSH molecules (Fraternale et al., 2006) and/or glutathione precursors like N-acetyl cysteine (NAC), glutamine, cysteine (cystine) and glycine, as well as nuclear factor erythroid 2 p45related factor 2 (Nrf2) inducers like sulforaphane can enhance glutathione production and increase nuclear Nrf2 translocation and antioxidant response element (ARE) transcription (Komaravelli and Casola, 2014
Arsenite-induced apoptosis is prevented by antioxidants in zebrafish liver cell line