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If you have a history of hereditary angioedema, severe chronic urticaria, or recurrent anaphylaxis, the Frontiers authors recommend hormone-aware multidisciplinary care and a careful evaluation before initiating estrogen-containing therapy

Long-chain acyl-CoA synthetase family member 4 (ACSL4) facilitates the incorporation of PUFAs, including arachidonate and adrenate, into cellular membranes (82)

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