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First, antioxidant properties allow alpha-lipoic acid to neutralize free radicals and reduce oxidative stress, which is linked to damage that can increase heart disease risk ( Second, its been shown to improve endothelial dysfunction a condition in which blood vessels cannot dilate properly, which also raises the risks of heart attack and stroke ( Whats more, a review of studies found that taking an alpha-lipoic acid supplement lowered triglyceride and LDL (bad) cholesterol levels in adults with metabolic disease ( Summary Alpha-lipoic acid has strong antioxidant properties, which may reduce inflammation and skin aging, promote healthy nerve function, lower heart disease risk factors, and slow the progression of memory loss disorders

doi: 10.1111/sms.13592 89 MontuoriPLopertoIPaoloCDi DatoCDe RosaACirilloTet al

A list of primers and plasmids are provided as separate Supplementary Data 1

2021;16:e20

J Biomech Eng