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Final Thoughts So, where does that leave the question of how long a B12 shot lasts

25 Folate Duration of therapy Patients with pernicious anemia require lifelong therapy, while patients with malabsorption require treatment until underlying condition or diet is corrected

People with documented malabsorption disorders including Crohns disease, celiac disease, or those whove had portions of stomach or small intestine removed need direct delivery

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