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Inject subcutaneously at a clean, rotated site abdomen, thigh, or upper arm For how to manage any side effects during titration, see our [semaglutide side effects guide](/guides/semaglutide-side-effects-how-to-manage)

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Vehicle interiors can reach 60 degrees Celsius (140 degrees Fahrenheit) within an hour on a sunny day, even when outside temperatures seem moderate