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Increases in resting heart rate are a recognised class effect of incretin-based therapies and have been reported with GLP-1 receptor agonists more broadly, as reflected in the Summary of Product Characteristics (SmPC) for licensed agents such as semaglutide (Wegovy) and liraglutide (Saxenda)

Creatine is necessary for all muscular function, and thus supports normal functioning of the heart and circulatory system

Neurological impact of vitamin B12 deficiency