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Ionizing radiation generates reactive oxygen species in tumor cells, targeting their DNA and thereby offering therapeutic benefits against malignant tumors [73, 74]

Furthermore, t-distributed Stochastic Neighbor Embedding (t-SNE) clustering under disease conditions ( Figure 6B ) reveals pathological remodeling of renal cellular subpopulations in acute kidney disease (AKD) and CKD, establishing a foundation for exploring the cell-selective roles of ferroptosis during renal injury progression