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BPC-157 is not FDA-approved for any human therapeutic use

Opioid-Induced Hyperalgesia and Allodynia Opioid-Induced Hyperalgesia (OIH) occurs when an opioid analgesic paradoxically causes an increase in pain, or an increase in sensitivity to pain

Reduced proteoglycan synthesis may contribute to the risk of spontaneous rupture

A large 2011 study gave 690 infertile men selenium with vitamin E for at least 100 days, reporting improved sperm parameters in 52.6% and a 10.8% spontaneous pregnancy rate, but it had no placebo group, so its results can't be cleanly separated from chance or natural variation

Patients with copper allergy should avoid GHK-Cu