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IL-17: A Controversial Player in Vitiligo Pathogenesis and Treatment Numerous studies have shown a relationship between IL-17 levels and melanocyte activity, indicating that it may play a role in the pathophysiology of vitiligo

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Symptoms include swollen and deformed joints

Additionally, patients receiving treatments affecting bone marrow function need careful monitoring during therapy

Prevention of cardiorenal complications and beyond With the improvement in the management of cardiovascular risk factors, a progressive decline in the annual incidence rate of cardiovascular morbidity and mortality has been observed in both the general population and the diabetic population over the past decades