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AI and AI-assisted tools statement During the preparation of this manuscript, the AI tool ChatGPT (GPT-5, released 2025-08-07) was used to generate Figure 1 and the Graphical Abstract and to improve the readability and language of the manuscript

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Beyond sleep, it influences neurotransmitter activity, hormonal rhythms, circadian behavior, and stress responses, suggesting potential therapeutic uses for sleep disorders, pain, and withdrawal syndromes