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Description

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Human hepatic microsomal cytochrome P450 enzymes metabolize 4-OH-TAM and 3-OH-TAM to produce the further oxidized metabolite, 3,4-dihydroxytamoxifen (3,4-diOH-TAM) 7,8

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This led us to uncover a crucial link between mut-p53 and cellular redox modulation

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43 EconomouM.PappasG

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