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Roth JA, Swisher SG , Fang B, Ji LX, Mukhopadhyay T, Ramesh R, Templeton N

Since growth hormone signaling drives cellular proliferation and protein synthesis in fibroblasts, this amplification creates a stronger repair response

J Korean Med Sci 18: 637640

TB-500 is commonly studied for its role in enhancing cell migration and angiogenesis , two processes that are important in wound healing, tissue remodeling, and structural repair

These metabolic signatures can separate MoA classes across a compound series, prioritise hits from phenotypic screens, and generate mechanistic hypotheses for subsequent validation by metabolic pathway drug response profiling or orthogonal proteomics approaches