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Nevertheless, studies utilizing more specific biomarkers of vitamin B 12 status, including measures of holo-transcobalamin and methylmalonic acid, have shown more consistent results and a trend towards associations between poor vitamin B 12 status and faster cognitive decline and increased risk of Alzheimers disease (82-86)

Treat these numbers as research-context structure only

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Individuals over the age of 50 years should augment their dietary intake with vitamin B 12 from supplements or fortified foods because of the increased likelihood of food-bound vitamin B 12 malabsorption with advanced age

Every bioavailability and half-life number above comes from rodent and cell-culture work