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Postmenopausal osteoporosis (type I): After menopause, women experience a sudden drop in estrogen levels, a significant increase in osteoclast activity, accelerated bone resorption, insufficient osteoblast activity, and rapid loss of bone mass (30% -50% loss after 5-10 years of menopause), mainly in the lumbar spine and hip

Although dipoledipole interactions can be quite strong, they involve the attraction of partial charges, which are smaller in magnitude than the full charges in ionion interactions

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